منابع مشابه
Side effects of vasodilator therapy.
Vasodilating antihypertensive drugs have in common the capacity to activate the peripheral sympathetic nervous system through the carotid sinus baroreceptor reflex mechanism, thereby increasing heart rate, renin release, and sodium and water retention. They differ in their tendencies to augment cardiac output and to relieve or precipitate cardiac failure and arrhythmias. Vasodilating antihypert...
متن کاملSide effects of amrinone therapy.
We gave intravenous amrinone to 40 patients in heart failure, and oral amrinone to 18 patients. Acute intravenous administration caused a significant reduction in mean blood pressure and this was severe enough to require correction by plasma infusion in five patients. Oral amrinone was accompanied by thrombocytopenia in 10 patients but no complications were associated with the low platelet coun...
متن کاملAcute and Long-term Effects of Vasodilator Therapy
The acute hemodynamic response to vasodilators in patients with chronic heart failure has been well characterized, but less is known about the long-term hemodynamic effects of vasodilator therapy. We measured hemodynamic variables at rest and during upright exercise in 11 patients during the initiation of therapy with oral hydralazine and sublingual isosorbide dinitrate and, in eight of these, ...
متن کاملGlucocorticoid therapy: minimizing side effects.
OBJECTIVE To describe the main undesirable side effects of glucocorticoid therapy, mechanisms of action and the necessary measures to minimize side effects. SOURCES Author's experience, supplemented with papers published in MEDLINE. SUMMARY OF THE FINDINGS The principles for minimizing undesirable side effects of glucocorticoid therapy include: a) only use glucocorticoids if they are essent...
متن کاملSide effects with amiodarone therapy.
Amiodarone hydrochloride is increasingly being used in the treatment of ventricular and supraventricular arrhythmias. Although a highly effective anti-arrhythmic agent, its use is restricted by the high incidence of side effects. To elucidate the value of monitoring serum level of both the parent drug and its active metabolite in predicting the occurrence of side effects, the investigators exam...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1988
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.11.3_pt_2.ii34